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GFP-Rab11A intracellular movement in IAV [A/WSN/33(H1N1)] infected A549 cells

dataset
posted on 2019-11-07, 18:04 authored by Amar BhagwatAmar Bhagwat, Seema LakdawalaSeema Lakdawala
TIFF series of diSPIM datasets, fused and deconvolved, from A549 GFP-Rab11A cells infected with influenza A virus [A/WSN/33(H1N1)]. Each TIFF file is a full cell volume of 50 planes, with isotropic resolution of 330nm, each .zip file is an independent replicate with at least 1 or 2 cells analyzed for 3D tracking of cytoplasmic foci with 500 time stamps. Analysis of these data correspond to data presented in Figure 5 and Supplementary Figure 10.

Figure 5: Effect of viral infection on Rab11A motion: comparing RSV infection with IAV (WSN) infection.

Supplementary Figure 10: Impact of viral infection on the transport of GFP-Rab11A.

Funding

Visualization of Influenza Viral RNA Assembly

National Institute of Allergy and Infectious Diseases

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Visualizing Influenza Viral RNA Packaging

National Institute of Allergy and Infectious Diseases

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The Role of Pathogen-Environment Interactions in the Pandemic Potential of Influenza

National Institute of Allergy and Infectious Diseases

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Intramural research program of the National Institute of Biomedical Imaging and Bioengineering (NIBIB)

American Lung Association Biomedical Research Award (RG-575688)

New Initiative Award (KA2018-98552) from the Charles E. Kaufman Foundation, a supporting organization of The Pittsburgh Foundation

History

Select an IC:

  • AI - National Institute of Allergy and Infectious Diseases (NIAID)

Is this associated with a publication?

  • Yes

I confirm there is no human identifiable information in this dataset.

  • Yes