EAGeR_CRP_EWAS_supp_tablesAtoG.zip (50.9 kB)

Supplemental Tables A to F for "Cord blood DNA methylation reflects cord blood C-reactive protein levels..."

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posted on 22.06.2020 by Edwina Yeung, Weihua Guan, Xuehuo Zeng, Lucas Salas, Sunni Mumford
Results using EPIC microarray to investigate maternal CRP in the pregnancy and delivery with cord blood DNA methylation. Results from model 1 adjusting for maternal age, smoking, income, pre-pregnancy BMI, and plate. Model 2 additionally adjusts for cell type distribution using the cord blood reference as published by Bakulski et al. 2016. Model 3 adjusts for model 1 covariates and cell type distribution using the cord blood reference published by Gervin, Salas et al. 2019. Results are from first trimester (week 8), second trimester (week 20), third trimester (week 36), cord blood, cumulative (AUC) or persistent (extreme tertiles) CRP.

Supports the publication:
Yeung, E.H., Guan, W., Zeng, X. et al. Cord blood DNA methylation reflects cord blood C-reactive protein levels but not maternal levels: a longitudinal study and meta-analysis. Clin Epigenet 12, 60 (2020). https://doi.org/10.1186/s13148-020-00852-2

Funding

HHSN267200603423

HHSN267200603424

HHSN267200603426

HHSN275201300023I-HHSN2750008

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  • HD - Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

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