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Supplementary Data for Effects of Age and Knee Osteoarthritis on the Modular Control of Walking: A Pilot Study
figure
posted on 2020-05-27, 00:09 authored by Sarah RoelkerSarah Roelker, Rebekah R Koehn, Elena J Caruthers, Laura C Schmitt, Ajit MW Chaudhari, Robert A. SistonThe module activation timing profiles and
muscle weightings of the individuals in the two, four, five, and six module
groups were not statistically analyzed because each of these module groups
contained just one participant from at least one population. The modular control results for these module groups are presented here for completeness along with the EMG activation patterns organized by module group.
Supplementary data for manuscript under review: Roelker SA, Koehn RR, Caruthers EJ, Schmitt LC, Chaudhari AMW, Siston RA. Effects of Age and Knee Osteoarthritis on the Modular Control of Walking: A Pilot Study.
Abstract: Older adults and individuals with knee
osteoarthritis (KOA) often exhibit reduced locomotor function and altered
muscle activity. Identifying age- and KOA-related changes to the modular
control of gait may provide insight into the neurological mechanisms underlying
reduced walking performance in these populations. The
purpose of this pilot study was to determine if the modular control of
walking differs between younger and older adults without KOA and adults with
end-stage KOA. Kinematic, kinetic, and electromyography (EMG) data were
collected from ten younger (23.9 ± 2.8
years) and ten older (62.4 ± 2.6 years) adults without KOA and ten KOA patients
(63.5 ± 3.4 years) walking at their self-selected speed. Separate
non-negative matrix factorizations determined the number of modules required to
reconstruct each participant’s EMG.
There was no significant difference (p
= 0.056) in the number of required modules between younger adults (4.1 ± 1.0), older adults without KOA (3.4 ± 0.8), and KOA patients (3.1 ± 0.6). However,
a significant association between module number and walking speed was observed
(r = 0.401; p = 0.028) and the KOA patients walked significantly
slower (1.01 ± 0.16 m/s) than the younger adults (1.24 ±
0.18 m/s; p = 0.026). In addition, KOA patients exhibited
altered module activation timing profiles and composition (which muscles are
associated with each module) characterized by increased muscle co-activity compared
to unimpaired younger and older adults who required the same number of modules.
Thus, disease-related changes in neuromuscular control strategy may be
associated with functional deficits in KOA patients
Funding
Using Intraoperative Measurements to Predict Postoperative Outcomes of TKA
National Institute of Arthritis and Musculoskeletal and Skin Diseases
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- AR - National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
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