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Calculator for Sampson LDLC plus Lipoprotein Phenotype

software
posted on 17.03.2020 by Maureen Sampson, Rami A. Ballout, Daniel Soffer, Anna Wolska, Sierra Wilson, Jeff Meeusen, Leslie J. Donato, Erica Fatica, James Otvos, Eliot A. Brinton, Robert S. Rosenson, Peter Wilson, Marcelo Amar, Robert Shamburek, Sotirios K. Karathanasis, Alan T. Remaley

· A new method for the classification of lipoprotein phenotypes is described, which can categorize patients into all the Fredrickson-like phenotypes except for Type III.

· The new method can be readily used to assign lipoprotein phenotypes based solely on the results of a standard lipid panel.

· It was validated by a commercial NMR lipoprotein profile and by agarose gel electrophoresis/beta-quantification in a large number of subjects.

· Lipoprotein phenotyping can aid in the prognosis and help direct clinical management for patients with dyslipoproteinemias.

History

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  • HL - National Heart, Lung, and Blood Institute (NHLBI)

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