GFP-Rab11A intracellular movement in RSV infected A549 cells

2019-11-07T18:04:31Z (GMT) by Amar Bhagwat Seema Lakdawala
TIFF series of diSPIM datasets, fused and deconvolved, from A549 GFP-Rab11A cells infected with Respiratory Syncytial Virus. Each TIFF file is a full cell volume of 50 planes, with isotropic resolution of 330nm, each .zip file is an independent replicate with at least 1 or 2 cells analyzed for 3D tracking of cytoplasmic foci with 500 time stamps. These data correspond to Supplementary Movie 9 and analysis of these movies provided data presented in Figure 5 and Supplementary Figure 10.

Supplementary Movie 9: A549 GFP-Rab11A cells infected with RFP-expressing RSV.

Figure 5: Effect of viral infection on Rab11A motion: comparing RSV infection with IAV (WSN) infection.

Supplementary Figure 10: Impact of viral infection on the transport of GFP-Rab11A.