Suppl_Table_9_Genes_DMR_on_TSS.xlsx (367.48 kB)

Supplemental Table 9: List of genes showing differential promoter methylation in chicken embryonic gonads with various degrees of feminization after in ovo exposure to ethynylestradiol

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posted on 20.10.2020, 21:27 by Toshihiro Shioda, Keiko Shioda, Junko Odajima, Bianca Cordazzo, Misato Kobayashi, Mutsumi Kobayashi

Supplemental Table 9 supporting: Keiko Shioda et al. “Transcriptomic and epigenetic preservation of genetic sex identity in estrogen-feminized male chicken embryonic gonads”
Supplemental Table 9: Genes with differentially methylated regions on transcriptional start sites.

Chicken embryos (29 total) were exposed to 20 microgram/egg ethynylestradiol or vehicle oil emulsion from incubation day 6, and their gonads were collected on day 19. This table shows list of genes showing differemtial promoter methylation in chicken embryonic gonads showing various degrees of feminization after exposure to ethynylestradiol determined by RNA-seq. Induction or suppression comparing various degrees of feminization scores (FS= 0,1,2,3) are shown in the tag labels.


This table shows 6 groups of TSS linked to differentially methylated genes (TDMGs) – namely, FS0 > FS3 (demethylated in FS=3 normal ovaries but not in FS=0 normal ZZ-testes; 341 TDMGs), FS0 < FS3 (3243 TDMGs), FS0 > FS1/2 (927 TDMGs), FS0 < FS1/2 (5352 TDMGs), FS3 > FS1/2 (6535 TDMGs), and FS3 < FS1/2 (1696 TDMGs).

Funding

Roles of Nuclear Receptors in Generation of Heritable Epimutations in Germ Cells

National Institute of Environmental Health Sciences

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Transgenerational obesity caused by ancestral exposure to obesogens in utero: changes in germline genomic architecture, roles of gonadal somatic cells, and metabolomic analysis of sexual dimorphism

National Institute of Environmental Health Sciences

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Developmental Gene-Environment Interactions and Premature Ovarian Failure

National Institute of Environmental Health Sciences

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